- Andrew Ramirez (Dexter Nolen)
- Anna Maganini (Lynette Bradley, Peggy Nolen)
- Arthur Russell (Doctor Xander Crowe)
- Ben Boodman (Mister Carrefour, Chip Drexal)
- Cheyenne Bsaies (Lemora Haskell, Katrina Edison)
- Chris Blaylock (Doctor Pete Meno)
- Dave Johnston (Deputy Drexal, Jonathan Kitter)
- Joe J. Thomas (Hank Mason, Phineas Thibert)
- Joy Vanides (Sister George)
- Koralee Nickarz (Deidre Frost, Emily Saunders)
- Nicole Rayburn (Harmony Barrister)
- Peter Dirksen (Jimmy Details, Jonesy)
- Rob Grindlinger (Sheriff Bradley, Cedric Bloomington, Don Marino)
- Robert W. Allen (Special Agent Voitek)
- Samantha Turk (Henrietta “Henry” Howe)
- Scott Olynek (Jacob Kitter)
- Sonia Perozzi (Sparrow, Rachel Nolen)
- Zachary Foulkes (Brent Saunders, Charles Edison)